منابع مشابه
Genetic rescue to the rescue.
Genetic rescue can increase the fitness of small, imperiled populations via immigration. A suite of studies from the past decade highlights the value of genetic rescue in increasing population fitness. Nonetheless, genetic rescue has not been widely applied to conserve many of the threatened populations that it could benefit. In this review, we highlight recent studies of genetic rescue and pla...
متن کاملCLIPs to the rescue
Suicide attempt linked to breakdown he Golgi apparatus breaks down temporarily to segregate into daughter cells during mitosis, but during apoptosis the organelle fragments irreversibly. On page 637, Chiu et al. report that cleavage of a critical tethering protein during apoptosis not only drives the fragmentation of the Golgi apparatus, but also appears to help propagate the apoptotic signal. ...
متن کاملROS to the rescue.
OVERPRODUCTION OF REACTIVE OXYGEN SPECIES (ROS) in biological systems has been associated with the initiation or aggravation of diverse pathological states (14, 19). The presumed mechanism is through the ability of ROS to induce biochemical alterations in macromolecules such as DNA, lipids, and proteins (4, 14, 17). It has been known for some time that ROS, produced physiologically by leukocyte...
متن کاملPlasticity to the Rescue
The balance between excitatory and inhibitory inputs is critical for the proper functioning of neural circuits. Landau and colleagues show that, in the presence of cell-type-specific connectivity, this balance is difficult to achieve without either synaptic plasticity or spike-frequency adaptation to fine-tune the connection strengths.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2006
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd2139